E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

Evo 2 now includes information from humans, plants, and other eukaryotic species to expand its capabilities in generative functional genomics.

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

Jumbo phages utilize a complex protein import system, with Imp1 as a key gatekeeper, to transport proteins into their ...

Researchers at Oregon Health & Science University have developed the first transgenic nonhuman primate model—genetically ...

Molecular communications in the bloodstream is a promising area of research, since the bloodstream has the ability to ...

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from ...

The model calculations in the present study show that proteins are therefore preferably synthesized in the branched, tapering ...

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers found that the neuronal energy conservation program determines the location and ...

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the ...