Panelists discuss how chronic neuroinflammation involves distinct mechanisms from acute relapses—including microglial ...

New research reveals that Alzheimer's disease may impair nerve function not by reducing myelin, but by altering the proteins ...

The disruption of axons—the thread-like part of nerve cells that transmits electrical signals—is associated with Alzheimer's disease. One way axonal function may be hindered is through damage to the ...

Nerves are coated in myelin, but have tiny gaps called “nodes of Ranvier” where the nerve is exposed to boost signals. Right next to these gaps are “paranodes,” where the myelin sticks tightly to the ...

While peripheral neuropathies have conventionally been classified into demyelinating or axonal, recent studies have proposed a novel concept, namely a ‘nodopathy’, whereby microstructural changes ...

Egawa et al set out to determine which factors regulate this differential node spacing. They do this by using immunohistological analyses to test the correlation of node spacing with morphological ...

The study, titled “ CSF Proteomics Reveals Changes in Myelin and Synaptic Biology Following Spectris™ Treatment,” offers compelling evidence of Spectris™’ ability to modulate core biological pathways ...

The physiological significance of the node of Ranvier is now well known. The histological delineation of its length, however, still remains uncertain. Should it be identified as the gap between the ...

Key features of peripheral nerve myelination were observed, including development of myelin segments and nodes of Ranvier, both critical for nerve impulse transmission.

In neuroscience, it is of interest to consider all possible modes of information transfer between neurons in order to fully understand processing in the brain. It has been suggested that photonic ...