Rimegepant, or Nurtec, is one of several drugs known as gepants that bind to the CGRP receptor. The drug, an oral tablet rather than a shot, was approved as a treatment for acute migraine in ...

There are two types of these drugs: monoclonal antibodies (mAbs) and small-molecule antagonists (gepants). MAbs are injectable medications used for long-term migraine prevention and management ...

one of the main neuroinflammatory molecules implicated in migraine. The monoclonal antibodies (mAbs) either bind to the CGRP molecule or to the receptor, blocking CGRP from attaching. Gepants work ...

Migraine disrupts daily life with invisible neurological pain, causing physical, emotional, and cognitive struggles that go ...

It was 2021 and she heard a scientist on the radio discussing the promise of gepants, a class of drug that for the first time seemed to prevent migraine attacks. West followed news about these ...

While both gepants and triptans bind to the blood vessel ... was safe for patients with migraine, with no new concerns identified.

The news has been welcomed by the Migraine Trust, which said that - unlike triptans, NSAIDs, and other painkillers - oral 'gepants' like Vydura don't seem to cause medication overuse headache.

Dr Shobha concluded, "A deeper understanding of migraine mechanisms has led to the development of targeted therapies, Triptans, serotonin receptor agonists, ditans, gepants, CGRP receptor ...

Have you ever had such a terrible headache that you wondered whether it could be something more? Well, maybe it is a migraine. There are some key differences between a headache and a migraine, and the ...

Research suggests that people with migraine may be more likely to develop ... like triptans and gepants. Depending on the type of headache you experience, a doctor may also prescribe preventive ...