Myelin is a concentrically laminated membrane structure surrounding an axon around which lamellae (or cellular protrusions) repeat radially at a period of about 12 nm (Waxman, Kocsis & Stys 1995 ...
Additionally, removing cholesterol from the neuron’s membrane made it less stiff and more fluid-like, altering the axon’s shape and reducing pearling. Based on these results, Watanabe set out to test ...
Opening and closing ion channels changes the membrane potential. When the neuron is triggered, it activates voltage-gated sodium channels at the beginning of the axon. This causes an influx of ...
Scale bar, 20 μm. (C) The neuronal axon is a long membrane-bounded extension, in which neurofilaments (a class of intermediate filament in neurons) form a structural matrix that embeds ...
The ligand Netrin mediates axon guidance through a combination of haptotaxis over short distances and chemotaxis over longer distances.
The speed of the action potential isn't constant, they assert, but modulated by changes in the size of the nano-pearls, which in turn are caused by mechanical changes in the axon's membrane and ...