Hence, researchers often simulate the brain as a network of coupled neural masses, each described by a mean-field model. These models capture the essential features of neuronal populations while ...

Joseph Arboleda-Velasquez of Harvard Medical School praised the results. “Ye’s group has now provided compelling evidence showing increased binding affinity of ApoE3 Christchurch for tau and its ...

The transgene is under the control of the neuron-specific murine Thy-1 promoter. The parental origin of the transgenes was shown to influence AD-related pathology in another model, 5xFAD (C57BL6), in ...

A pathway once considered fundamental in Alzheimer’s disease is being studied intensely again, and may soon result in safer, ...

Now, scientists have discovered a new mechanism by which these crucial supporting players detect and respond to neuron damage. Published in Nature Communications, the study describes how two key ...

Pain is an example of an important sensory neuron. When you feel pain from a hot pan or a sharp pin, you are sending sensory information via sensory neurons up to the brain. The flow of electrical ...

While previous research has highlighted the key role of the cNTS in food intake regulation, the unique contribution of the different neuron subtypes within this brainstem region and the mechanisms ...

which have been known to link to NMJ degeneration and distal axonopathy in pathology. In this study, we demonstrated that Bet1L knockdown induced NMJ denervation, motor dysfunction, and motor neuron ...

The Canyon Neuron has long been the German brand’s most approachable do-it-all trail bike. Sitting in between the lightweight Lux Trail and the bigger travel Spectral, the Neuron aims to strike a ...