Joseph Arboleda-Velasquez of Harvard Medical School praised the results. “Ye’s group has now provided compelling evidence showing increased binding affinity of ApoE3 Christchurch for tau and its ...

The cellular and molecular mechanisms that ensure the elaborate connection and function of the nervous system can then be dissected with single neuron ... R. Histology of the Nervous System ...

A Columbia-led study uncovers how gliomas cause seizures and cognitive impairments by disrupting brain activity. Using ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

A study led by Dr. Peter Canoll's lab, in collaboration with researchers at Columbia University Irving Medical Center, ...

The transgene is under the control of the neuron-specific murine Thy-1 promoter. The parental origin of the transgenes was shown to influence AD-related pathology in another model, 5xFAD (C57BL6), in ...

Despite anecdotal reports of exceptional cases, ALS is a condition with relentless progression, and riluzole, the single disease-modifying drug licensed for the condition, provides only an ...

Studying the cell is a difficult and time-consuming process, but scientists have pinpointed generative AI as a potential way to make it easier. The idea is to develop an AI virtual cell that would ...

Neuropeutics Inc announces a collaboration with LifeArc to develop a new small molecule for the treatment of motor neuron disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

This means that a neuron spends more than 95 percent of its ... “We've been able to piece together the full trajectory of the pathology as it unfolds over decades in individual neurons, and ...