Between two adjacent myelin segments, there are approximately 1-μm-long gaps called nodes of Ranvier (Figure 1A and E). At the nodes, the axon is exposed to the extracellular space. How is the ...

a molecule specifically expressed in myelin. Nodes of Ranvier (arrows) are stained in green by an antibody to nodal molecule beta-IV spectrin.

Laminin receptors are also important for myelin and nodes of Ranvier to achieve the correct length, thickness, architecture and stability. Patients lacking laminins have abnormally thick and instable ...