The long-running show "South Park" came back hard, with a Season 27 premiere lambasting their new partner Paramount and President Donald Trump.

The comedy duo were asked if they'd anticipated such a strong reaction to the premiere during a Comedy Central panel at San Diego Comic-Con.

After the explosive 'South Park' Season 27 premiere, Stephen Colbert reveled in the show's insults at Trump and fellow parent company Paramount.

A wild season premiere of "South Park" showed Donald Trump in bed with Satan and tore into Paramount for canceling Stephen Colbert's "Late Show."

Season 27 premiered Wednesday on Comedy Central with an episode titled "Sermon on the 'Mount" -- as in Paramount

The day after the "South Park" Season 27 premiere, the show's creators Trey Parker and Matt Stone participated at a Comedy Central's Comic-Con animation panel. They sat by "Beavis and Butt-Head" creator Mike Judge and "Digiman" creator Andy Samberg. Parker had just three words to say about the episode.

Paramount itself also wasn't safe from the ire of Parker and Stone. The episode also features a pair of animated "60 Minutes" anchors covering protests as they nervously praise Trump and insist they don't agree with the protesters, intimating that they might be worried he will sue again.

South Park” targeted President Trump and Paramount Global in its latest episode this week, poking fun at the president for targeting his enemies and at one point depicting him in bed

Comedy Central’s “South Park” recently struck a five-year deal with Paramount after a merger delayed the Season 27 premiere.

Did you miss controversial Season 27 premier of South Park? Here's how to watch and stream new episodes of the Comedy Central series.

The roasting comes right after Trey Parker and Matt Stone's $1.5 billion global streaming deal with the Comedy Central parent company